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First, we did not look at effectiveness of these drugs the values reported here were found prior to initiation of the prescriptions, and thus, cannot be used to infer drug effectiveness over time
5 Pharmacological effects of GIP, GLP-1 and their mimetics The pharmacological benefits of GIP, GLP-1, and their synthetic mimetics arise from their pleiotropic effects, encompassing at least five key functions: bolstering insulin secretion and survival of pancreatic -cells and modulating glucagon release by the pancreatic -cells in response to glycemic levels, acting on the satiety center in brain, slowing gastric emptying, regulating lipid and glucose metabolism through effects on adipose tissue and liver, and reducing systemic blood pressure
Supplement interactions are not well studied, and using more than one product at a time can increase the risk of side effects
Patients randomized to exenatide started on a dose of 5 mcg twice-daily for 4 weeks and then were escalated to 10 mcg twice daily
These medications require prescription, monitoring, and integration with lifestyle changes