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Greater retention of BA suggests that supplementation in a sustained-release format might lead to greater increases in muscle carnosine compared to an instant release (e.g., powder) formulation, although the authors did not measure muscle carnosine in this study

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Cha J-Y, Kim JY, Jung IJ, Kim MR, Melencion A, Alam SS, Kim W-Y (2014) NADPH-dependent thioredoxin reductase A (NTRA) confers elevated tolerance to oxidative stress and drought

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(20) It suggests that this powerful antioxidant may be more useful for older adults than for younger ones in preventing cellular damage

If the patient presents less than 8 hours after ingestion and the time of acute acetaminophen ingestion is known and the acetaminophen concentration is known: Use the Rumack-Matthew nomogram to determine whether or not to initiate treatment with ACETADOTE