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Description

doi:10.1161/CIRC.127.SUPPL_12.AMP90 18

Sato, A

Mechanism of Action The GLP-1 RAs correct 6 of the 8 components of the Ominous Octet (2): (i) they enhance insulin secretion (15,28,29) and (ii) inhibit glucagon secretion (15) leading to (iii) a reduction in hepatic glucose production (51)

But again, don't despair

Your body's peptide pathwaysthe intricate systems controlling appetite, energy use, and metabolic functionremain responsive to GLP-1 signaling even when hormonal fluctuations occur