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Topical numbing cream can be applied 2030 minutes before treatment for those who prefer additional comfort

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Encapsulated nanoparticles can help to solve the bioavailability limitation in biological systems, which occurs when sufficient concentrations of these compounds are not reached in the systemic circulation after eating or ingesting the compounds to express an antitumor effect (280, 375)

Commonly observed reactions include: Gastrointestinal: Nausea, vomiting, diarrhea, constipation, abdominal discomfort