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L.ChenF
Wulczyn, K
Cells undergoing ferroptosis show none of the classical morphological alterations associated with apoptosis, necroptosis, or autophagy (e expression is critical to protection against acute lung injury in mice
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In addition to KEAP1, other forms of regulatory proteins of NRF-2 have recently been discovered, such as the E3-Ubiquitin-ligase adaptor, and the -transducin repeats-containing protein (-TrCP), which can also be degraded by Glycogen Synthase Kinase 3 (GSK-3), phosphorylizing NRF-2 into its residue as serine in the Neh 6 domain, corresponding to the recognition of -TrCP [18] (Fig
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