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The investigators previously revealed that sales in womens tops sizes extra small (XS) and small (S) rose from 34% to 39% between 2022 to 2024, while tops marked L and XL dropped from 33% to 31% during the same time period

This may suggest that increased mitochondrial function likely plays a role in mediating the therapeutic effects of lithium and valproate treatments in BD

In the highest-dose group studied (12 mg once weekly), mean weight loss approached 17.5% of body weight over 24 weeks

Clinical observations show that roughly 30% of patients report nausea as their primary side effect during the initial adjustment

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Gastrointestinal side effects including nausea, reflux, and abdominal discomfort may indirectly disrupt sleep quality