They act as antioxidants, support gut bacteria, and some studies suggest they may enhance GLP-1 production and inhibit DPP-4 (an enzyme which breaks down GLP-1) [6]
It's also one of the queries where the answer is most easily misleading if you focus on the sticker price alone
Given the investigational nature of low-dose GLP-1 therapy for inflammation, identifying appropriate candidates requires careful clinical judgment and shared decision-making
Risk Factors to Be Aware Of Certain factors may increase your likelihood of experiencing this concern: Check your GLP-1 eligibility Use our free BMI Calculator to see if you may qualify for provider-reviewed GLP-1 therapy
Phase 3 TRIUMPH-4 trial The most recent Phase 3 results, announced in December 2025, tested retatrutide in people with obesity and knee osteoarthritis
53, 363367 (John Libbey, 1994)