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ACS Synth BiolEfficient Strategy for Synthesizing Vector-Free and Oncolytic Herpes Simplex Type 1 Viruses

Loss of appetite is common and may lead to weight loss, especially early on

Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2

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These include nausea (affecting up to 44% of patients), vomiting, diarrhoea, constipation, abdominal pain, and dyspepsia

This longevity of research interest is itself informative: compounds that fail to replicate across independent laboratories typically disappear from the literature within a decade