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The DSMB meets on an agreed timeline based on recruitment to review safety and efficacy data in a group-blinded fashion and may request unblinding of the data as needed to ensure subject safety

Thus, novel therapeutic approaches that exert renoprotective effects independently of these factors have been awaited

1 Introduction Life-sustaining activities are dependent on metabolism, and disturbances in metabolic functions (such as the metabolism of lipids, amino acids, glucose, proteins, electrolytes, and energy) can damage one or multiple organs (Kaelin and McKnight, 2013

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This decline substantially affects overall health and vitality

Beyond Glutathione Hence, this project could be extended in the future by including some of the other molecules involved in maintaining redox homeostasis