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297 p53 is significantly acetylated at the Lys (118) residue in a rat model of ischemia/reperfusion injury, which regulates p53 binding and accumulation at the Bax promoter

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Experimental frameworks assess nitric oxideassociated signaling, modulation of inflammatory mediators, and intracellular survival cascades including PI3K/Akt and ERK pathways within vascular cell models

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