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The MHRA ( Medicines and Healthcare products Regulatory Agency ) has two main application procedures: Simple Reclassification : This is a straightforward and quick procedure based on an analogous product (a medicinal product already on the UK market with the same active ingredient, route of administration, use, and a similar or higher strength/dosage)

They concluded that the esterified GSH derivative was effective in reducing melanin and tyrosinase activity and raised the pheomelanin/eumelanin ratio without affecting cellular viability

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Valentine, V., Goldman, J