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Comparison: MOTS-c + 5-Amino-1MQ Synergy vs Monotherapy Key Takeaways MOTS-c activates AMPK to increase mitochondrial function and fat oxidation, while 5-Amino-1MQ inhibits NNMT to preserve NAD+ poolstargeting complementary metabolic pathways
Your body uses B12 to build healthy blood cells and proteins and to metabolize fats and carbohydrates
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Vanessa Mack (Dean) and her team take a personalized approach by evaluating each patients health history, symptoms, and wellness goals
To inject correctly, use a sterile needle and syringe