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Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, et al

Mechanisms of Action and Therapeutic Rationale Physiological Basis of GLP-1 Action GLP-1, an incretin hormone, plays a crucial role in glucose metabolism and appetite regulation, influencing insulin secretion, insulin-sensitivity, and gastric emptying [15] [16]

These peptides are natural gastrointestinal hormones found in the GI tract released in response to eating

Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression

Brain-derived GLP-1 pathways are generally not activated unless metabolic balance is disrupted, such as under stress conditions

doi: 10.1007/s40256-024-00707-8 36 American Diabetes Association Professional Practice Committee