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Longitudinal analyses from the Phase 2 and Phase 3 trials show that the incidence of new-onset nausea and vomiting peaked during the first 4-8 weeks of treatment and then declined substantially during the maintenance phase

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GABAergic interneurons are known to exert an inhibitory role on glutamatergic neurons through the release of GABA

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Blzquez C., Casanova M.L., Planas A., del Pulgar T.G., Villanueva C., Fernndez-Aceero M.J., Aragons J., Huffman J.W., Jorcano J.L., Guzmn M