In the KK/TA-Ins2Akita mice treated with a combination of empagliflozin and rigagliptin, which provided greater reductions in glomerular albumin filtration and GFR, as well as higher urinary sodium excretion, the dual inhibition of SGLT2 and DPP-4 highly promoted distal tubule sodium delivery, compared with empagliflozin monotherapy
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
Multivariate statistical analysis was performed using MetaboAnalyst v5.0 (Xia Lab, McGill University, Montreal, Quebec, Canada
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