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When intestinal I/R injury occurs, the tight junctions between intestinal epithelial cells become compromised, leading to increased intestinal permeability, a phenomenon often referred to as leaky gut (Liu et al., 2023)

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Additionally, the researchers found that the epithalamin-treated patients exhibited reduced rates of: Coronary artery disease Hypertension Osteoarthritis Osteoporosis The researchers concluded that epithalon may be used for health maintenance and age-related pathology prevention in the elderly.

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This problem became important in the case of routine analysis which usually are dedicated for cohorts