One study on patients with major depressive disorder compared patients with hyperphagic versus hypophagic symptoms with healthy controls, finding differential effects of ghrelin depending on somatic symptom profile (Cerit et al., 2019)
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Ethical approval This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics (Additional file 1: Table S1 and Additional file 2: Fig
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To gain insight into the molecular mechanism of action of GLP-1 peptides, here we report the crystal structure of the full-length GLP-1 receptor bound to a truncated peptide agonist