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356,357 The extracellular domains of both CD43 and CD45 are heavily decorated with O-linked and N-linked carbohydrate moieties that often terminate in sialic acid

Hypoxia inducible factor-1alpha mediates the profibrotic effect of albumin in renal tubular cells

Altered B12 handling and reduced clearance in kidney disease, and both cellular release and reduced clearance in liver disease, can raise B12, so supportive renal or hepatic findings make those causes plausible

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