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This is exactly what's often lost when appetite (and food volume) drops

Most patients notice decreased appetite within 2448 hours, but measurable weight loss typically appears after 714 days as reduced calorie intake compounds

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Weighing Benefits Against Gastrointestinal Risks The documented benefits of GLP-1 therapysustained weight loss, improved metabolic markers, and cardiovascular risk reductionsubstantially outweigh the extremely low incidence of appendicitis reported in clinical populations