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Tyrosinase controls the most important step in melanin production which is the conversion of tyrosine to L-DOPA

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Approved uses and dosing context Across the class, FDA-approved indications include type 2 diabetes for most compounds, chronic weight management for Wegovy, Saxenda, and Zepbound, and obstructive sleep apnea in adults with obesity for Zepbound as of 2024

The proportion of patients with comorbidities associated with fracture risk such as T2D (26.7%), cardiac disease (16.3%), and liver disease (11.2%) was also reported

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Monitoring and Prevention Strategies Regular monitoring helps identify bleeding concerns early during Mounjaro treatment