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doi: 10.3389/fendo.2020.586529 140 BelkaidYHandTW

Longevity research examines factors that influence cellular lifespan and function over time

Importantly, glucose metabolism and insulin sensitivity were either unchanged or slightly improved, contrasting with the diabetogenic effects of growth hormone

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Without functional annotation, researchers are left with lists of genes or proteins that lack context, hindering efforts to understand molecular mechanisms of disease, identify drug targets, or explore phenotypic variation