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Metformin administration during early postnatal life rescues autistic-like behaviors in the BTBR T+ Itpr3tf/J mouse model of autism

Cancer Cell 4 , 3139 (2003)

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In in vitro cell experiments using 3T3L1 preadipocytes as a model, treatment with NNMTi significantly reduced preadipocyte differentiation efficiency and markedly downregulated the expression of adipocyte markers (such as PPAR and C/EBP) in a dosedependent manner

Three-dimensional (3D) cell culture: a valuable step in advancing treatments for human hepatocellular carcinoma