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Compound 35 significantly reduced the production of IL-6, IL-1, and TNF- in LPS-induced RAW 264.7 macrophages, with IC 50 values of 78.03 nM, 17.6 M, and 82.15 nM, respectively

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(2005) Fungal metabolite gliotoxin targets flavocytochrome b558 in the activation of the human neutrophil NADPH oxidase

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Additionally, ferroptosis is facilitated upon inactivation of the antioxidant enzyme GPX4 [161]

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