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The pharmacokinetic advantage is significant: systemic bioavailability of intranasal peptides is typically 1020%, but CNS bioavailability can reach 3060% because the compound travels directly along nerve sheaths into cerebrospinal fluid

NAD Defined: Nicotinamide adenine dinucleotide (NAD) is a coenzyme in all living cells

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Summary, a simple challenge remains: the existing treatments at present offer only symptomatic treatment but not reversal of disease