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doi: 10.1007/s00198-015-3279-7 11 Starup-LindeJHygumKHarslfTLangdahlBL

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Metformin treatment significantly increased AMPK phosphorylation while decreased the Akt phosphorylation, resulted in inhibition of proliferation and induction of apoptosis in the renal proximal tubule cells (143)

Using conditioned media, we were able to show that M1-M secretions impaired the establishment of HBV infection in hepatocytes, highlighting the relevance of previously published data [4]

After that, theyve completed the treatment portion of the protocol, and they could go on, if they needed, to any other treatments