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"Catecholamine reuptake inhibition causes weight loss by increasing locomotor activity and thermogenesis." Neuropsychopharmacology
However, therapeutic doses for treating deficiency range from high-dose oral supplements (1,0002,000 g daily) to intramuscular injections of 1 mg, particularly for pernicious anaemia or malabsorption conditions
Vitamin B12 has a good safety profile, but some important considerations include rare hypersensitivity reactions (including anaphylaxis) with injections, potential hypokalaemia during early treatment of severe deficiency, and possible cutaneous reactions
However, this was an in-vitro (petri dish) study
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