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Using medication slightly past expiration is probably safe but may be less effective due to degradation

7781,8386 Long-term exposure to these recurrent episodes of hypoxia-reoxygenation activate nicotinamide adenine dinucleotide phosphate-oxidase 2 that consumes oxygen through its generation of reactive oxygen species

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These findings suggest that metformins influence on AD risk may be mediated through non-genetic mechanisms rather than through direct genetic determinants

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