acetyl-l-carnitine deficiency in patients with major depressive disorder Frontiers The neuropsychopharmacology of acetyl-L-carnitine (LAC):

doi: 10.1016/s0025-6196(12)62109-0

Plasma carnitine rises after dosing, but muscle stores have barely begun to climb, so the recovery and fatigue benefits the trials measured are not yet expected to appear

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This formula has been chemically altered to avoid binding to proteins in the human body, and to increase the half life, approximately 20-30 hours