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At the agent-level, several individual GLP-1RAs demonstrated moderate to high certainty for MACE when compared with placebo, whereas certainty for other outcomes was generally low to moderate, reflecting wider confidence intervals and greater between-study heterogeneity (Supplementary Table S26)

Instead of treating heart disease, cancer, Alzheimers disease and other age-related conditions as separate problems, geroscientists argue they are linked by common biological processes, including chronic inflammation, impaired cellular repair, metabolic dysfunction and the accumulation of damaged cells

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