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Gao et al., 2015)

No changes in lean mass were detected after intervention with the different doses of GLP1/E (Fig

In the SURMOUNT-1 study, a phase 3 clinical trial in obese patients, randomized participants in a 1:1:1:1 ratio to tirzepatide (5, 10, 15 mg) or placebo over 72 weeks, significant weight reductions were observed at 72 weeks: 15.0% for 5 mg, 19.5% for 10 mg, 20.9% for 15 mg, compared to 3.1% for placebo [18]

As weight loss progresses , monitor your thigh tissue depth periodically

World J Gastroenterol (2018) 24:174865