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Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study
It strengthens the mucosal barrier, supports the microbiome, and may help improve symptoms in conditions like gastritis, IBS, or even leaky gut
Most people run protocols combining multiple peptides over extended timeframes
These results suggest that urinary excretion is the dominant route of elimination following IM administration of BPC157
[DOI: 10.1186/1471-2288-5-13] [DOI] [PMC free article] [PubMed] [Google Scholar] Hrbjartsson 2013 Hrbjartsson A, Thomsen AS, Emanuelsson F, Tendal B, Hilden J, Boutron I, et al
