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At 12 mg, the average increase was around 6.7 beats per minute, peaking around week 24 and declining toward baseline by weeks 36 to 48

In the brain, the interaction of GLP-1 or GLP-1RA with the GLP-1R additionally contributes to multi-level control of neuroplasticity mechanisms thus having potential cognitive and affective effects

However, it is important to note that our therapeutic approach is not a miracle cure either and successful treatment also requires lifestyle changes, including a healthy diet and sufficient physical activity

Adv Clin Exp Med 31(11):12651274

For tablets, your dose can be lowered or you can switch to a different type

But if those approaches have not yielded success, it is certainly worth looking closer at other solutions