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A lower lacunarity in SEMtreated OHT rats indicates that SEM may promote the preservation of a homogeneous and organized retinal vasculature, with fewer large gaps and irregularities in vessel distribution

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Specifically, women with PCOS have an increase in the expression of AGE and RAGE in the theca and granulosa cell layers, compared to healthy women [34, 64]

In another study, interleukin-6 levels were elevated in the fat from women with Dercum disease compared to women without lipedema supporting Dercum disease as an inflammatory disorder (226)