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The difference between 10mg and 15mg was relatively small (about 1 percentage point), which is why many people find their effective maintenance dose in the 7.5mg to 10mg range without needing to push to maximum

This vitamin b12 deficiency skin problems tend to cause darkening of the skin, patchy, especially on the hands, feet, and joints

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years