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Retatrutide is a NuSH-based triple agonistit targets GLP-1, GIP, and Glucagon receptors

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Intramuscular injection typically causes sharper pain during injection, more bleeding afterward, and sometimes a dull ache that persists for hours

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And these drugs, known as GLP-1 agonists, work both in the brain and the gut to give patients a sense of satiety and make them less hungry, improving many of the underlying concerns that lead to heart disease