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This synergizes with omega-3 to reduce intestinal permeability (LPS levels down) and strengthen gut-brain axis communicationexplaining why fish intake is more effective for depression than omega-3 supplements alone (319)

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Dopamine Release and Uptake Classically, dopaminergic neurons release dopamine when an action potential reaches the axon terminal, inducing dopamine-containing vesicles to fuse with the cell membrane and release dopamine via exocytosis (Liu and Kaeser, 2019)