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During this period, patients typically develop more sophisticated strategies for managing their treatment and lifestyle modifications
Their diabetic control and cardiometabolic risk factors like blood pressure and cholesterol also tend to revert to their previous state. Dr Tan highlights the Surmount-4 clinical trial that looked at the issue of weight regain after treatment with tirzepatide
Bagsvaerd, Denmark: Novo Nordisk A/D
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2.1.1 Calcium channel modulation Recent research has shown that exendin-4, a GLP-1RA, suppresses L-type voltage-gated calcium channels (L-VGCC) activity through a cascade involving cAMP/PKA, ryanodine receptors, and calmodulin (CaM)
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