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As shortages resolve, regulators are less willing to tolerate parallel supply channels for approved drugs

Novo Nordisk was the pioneer--winning a 2014 FDA-approval for liraglutide (Saxenda) as an obesity treatment, formulated as a once-daily subcutaneous injection

Sparmann, A

whereas Tresiba may be better suited for those seeking stable blood sugar control without frequent dosage adjustments and less likelihood of experiencing low blood sugar episodes

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This common gastrointestinal side effect occurs in approximately 8-30% of patients taking semaglutide (Ozempic, Wegovy, or Rybelsus) and is most pronounced during initial treatment and dose escalations