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There are a number of chemicals inside the mitochondria that function in an organized way to convert fatty acids and carbohydrates (in the form of glucose) to CO2

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Such findings underscore a central challenge in chemical biology: within highly interconnected and partially redundant redox networks, achieving absolute molecular selectivity is inherently difficultif not fundamentally unrealistic

In the UK and EU, these are included as warnings and precautions in the product information, rather than formal contraindications (unlike in the US, where they appear as boxed warnings and contraindications)