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Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes

Day 1: 100-200mg NAD IV (1-4 hrs) Day 4: 25mg NAD SQ Day 6: 25mg NAD SQ Daily: 250mg NR/NMN in the morning Week 2 We increase the SQ shots here to extend the life of the initial IV dose of NAD

The proposed mechanism described in papers that were later retracted is that it potentiates hepatocyte growth factor (HGF) signaling at the c-Met receptor, driving dendritic spine formation and synaptogenesis