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As for kidney diseases, autophagy may protect functions in both glomerular and tubular compartments by suppressing excessive inflammation and fibrosis in AKI, CKD, and DN (Kimura et al., 2017

EPR spectroscopy allowed recognizing the generation of reaction products of DMPO that derive from its reaction with superoxide (in its turn, recognized from its disappearance from the reaction mixture after incubation with superoxide dismutase)