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Mechanism of action : (34300194, 32794143) The primary mechanism might be via enhanced GABA signaling: Increases GABA synthesis
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Springer Nature Singapore, Singapore, pp 101116 Choudhary P, Upadhyay P (2023) Relevance of the antioxidative mechanism during plant-microbe interaction
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doi: 10.5966/sctm.2011-0052
Inhibitory activity of pycnogenol was also showed well against SAPK/ JNK, ERK1/2 and p38 MAP kinases, iNOS and COX-2 expression in synovial tissue and articular cartilage [27]
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