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Subsequent studies showed the favourable effect of GLP-1 on pancreatic islets as a stimulant for cell proliferation and survival as well as its inhibitory effect on cells and glucagon secretion, likely through paracrine mechanisms such as inhibitory factors released from cells and through stimulation of local cell somatostatin secretion [12]

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The disease processes driving weight gain do not resolve because weight decreases

[DOI] [PubMed] [Google Scholar] 45.Sacks D.B., Arnold M., Bakris G.L., Bruns D.E., Horvath A.R., Lernmark ., Metzger B.E., Nathan D.M., Sue Kirkman M

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But the accumulating, independently-verified data across multiple trials and populations says it will soon become one of the highest-efficacy options in obesity and diabetes medicine