CANTATA: Primary analysis of a global, randomized, placebo (Pbo)-controlled, double-blind trial of telaglenastat (CB-839) + cabozantinib versus Pbo + cabozantinib in advanced/metastatic renal cell carcinoma (mRCC) patients (pts) who progressed on immune checkpoint inhibitor (ICI) or anti-angiogenic therapies
The reason behind this is that they can enhance metabolic function, encourage fat export from the liver, and provide nutritional support
N Engl J Med 380(24):22952306 Kristensen SL, Rrth R, Jhund PS, Docherty KF, Sattar N, Preiss D et al (2019) Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials
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This is notably less pronounced than with GHRP-6 , which is famous for causing extreme, almost uncontrollable hunger
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