And dosing is just part of the confusion
The most common side effects are gastrointestinal, including nausea, vomiting, and abdominal pain
The FDA has approved these medications for adults with obesity or those who are overweight and have at least one related health condition, such as high blood pressure or type 2 diabetes
The total matters less than the timing, frequency, and amplitude of individual secretion events
Slowing Gastric Emptying : Extends digestion time, leading to more gradual nutrient absorption and improved blood sugar stability ( 1, 3 )
In a trial of semaglutide, people who switched to a placebo regained around 7% of their body weight over the following year, while those who kept taking the medication lost a further 8%