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Mol Metab 14:150157 Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J et al (2011) Native incretins prevent the development of atherosclerotic lesions in Apolipoprotein E knockout mice

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Advanced glycation end products-induced insulin resistance involves repression of skeletal muscle GLUT4 expression

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Distinguished as a potent non-enzymatic antioxidant and free radical scavenger, melatonin possesses the unique ability to neutralize free radicals independently of receptors, owing to its distinctive chemical structure [93]

The most common adverse events for both study treatments were gastrointestinal, and most were mild to moderate in severity, occurring primarily during dose escalation