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In particular, while several studies suggest that -3 PUFA consumption has protective effects on the development of autoimmune thyroiditis [122], others demonstrate that exposure to pollutants (especially heavy metals) that contaminate fish is associated with an increased risk of autoimmunity and thyroid dysfunction [121,124,125,126]

For example, one source puts intranasal DSIP as more patient-compliance friendly than injections

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10.1016/S0140-6736(19)30726-3 Lancet