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This is possible due to cysteine residues present on KEAP1 that can be oxidized and prevent the otherwise inevitable ubiquitination and degradation of NRF2

[DOI] [PubMed] [Google Scholar] 14.Moghaddas A, Dashti-Khavidaki S

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Experiments in Pemt +/+ and Pemt / mice, provided by LKS Centre for Health Research Innovation (89), were approved by the University of Albertas Institutional Animal Care Committee

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