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That said, it is likely that GLP-1 pills like Orforglipron will offer patients greater choice and flexibility

FDA approval ensures that the medications have been thoroughly tested, but ongoing research continues to monitor their long-term effects

Notably, GLP-1 RAs also tend to promote growth of genera known for supporting gut barrier integrity (such as Akkermansia ), further hinting at a positive remodeling of the gut ecosystem (34, 35)

42 LessingF.KniemeyerO.WozniokI.LoefflerJ.KurzaiO.HaertlA.et al (2007)

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