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The short half-life of native GLP- 1-based therapy in the circulation (approximately two minutes after intravenous administration and one to five hours after subcutaneous administration) posed a problem during its early development [9]

NAC NAC contains an acetylated amino group

Un hallazgo reciente y an preliminar (acoplamiento molecular) propone adems activacin de SIRT1, pero todava sin validacin clnica

The contribution of incretins to insulin secretion is particularly remarkable: in healthy individuals, GLP-1 and GIP account for up to 60% of postprandial insulin secretion (Salehi et al., 2010)

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Zhao, X.-B